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🤯 GPT-5's Medical Reasoning Prowess: GPT-5 just passed the hardest medical exam on Earth, and outscored doctors

13 min • 15 augusti 2025

🤯 GPT-5's Medical Reasoning Prowess: GPT-5 just passed the hardest medical exam on Earth, and outscored doctors

Listen at https://rss.com/podcasts/djamgatech/2168086

or at https://podcasts.apple.com/us/podcast/gpt-5s-medical-reasoning-prowess-gpt-5-just-passed/id1684415169?i=1000722136023

We’re not talking marginal gains. We’re talking GPT-5 beating licensed doctors, by a wide margin, on MedXpertQA, one of the most advanced medical reasoning benchmarks to date.

Here’s what’s wild:

👉+24.23% better reasoning

👉+29.40% better understanding than human experts

👉Text-only? Still crushing it:

- +15.22% in reasoning

- +9.40% in understanding👉+24.23% better reasonin

And this isn’t simple Q&A. MedXpertQA tests multimodal decision-making: clinical notes, lab results, radiology images, patient history. The whole diagnostic picture.

GPT-5 didn’t just pass, it out diagnosed the people who wrote the test.

Read the paper here: Capabilities of GPT-5 on Multimodal Med: https://arxiv.org/pdf/2508.08224

Why this matters:

→ Clinical reasoning is hard, it involves uncertainty, ambiguity, stakes

→ GPT-5 is now showing expert-level judgment, not just recall

→ This could be a turning point for real-world medical AI deployment

We’ve crossed into new territory.And we need to ask:If AI can reason better than experts, who decides what “expert” means now?

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Sources:

  • Excerpts from "GPT-5's Medical Reasoning Prowess" (Informal Summary)
  • "Capabilities of GPT-5 on Multimodal Medical Reasoning" (Full Research Paper - arxiv.org/pdf/2508.08224)

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