In this episode you'll learn why we prescribe baby aspirin, who should take it and how much.
Low-dose aspirin (81 mg/d a.k.a. baby aspirin) reduces the frequency of preeclampsia, as well as related adverse pregnancy outcomes (preterm birth, growth restriction), by approximately 10-20%.
Low-dose aspirin should be started after 12 weeks and ideally before 16 weeks and continued daily until delivery.
Low-dose aspirin is recommended for:
- Pregnant individuals with one or more of the following risk factors:
- History of preeclampsia
- Carrying more than one baby (twins, triplets, etc)
- High blood pressure that was present before pregnancy (chronic hypertension)
- Type 1 or 2 diabetes that was present before pregnancy
- Kidney disease
- Autoimmune disease (ie, systemic lupus erythematous, antiphospholipid syndrome)
Pregnant individuals with 2 or more of the following risk factors:
- Having your 1st baby
- Obesity (ie, body mass index > 30)
- Family history of preeclampsia (ie, mother or sister)
- Black race (as a proxy for underlying racism)
- Lower income
- Age 35 years or older
- Personal history factors (eg, low birth weight or small for gestational age, previous adverse pregnancy outcome, >10-year pregnancy interval)
- In vitro fertilization
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