Opioid-induced respiratory depression in paediatrics: a review of case reports

Professor Albert Dahan, head of the Anesthesia and Pain Research Unit at Leiden University Medical Centre, talks about why this common and dangerous phenomenon is under-reported in the literature and as a result, why he has taken this unusual investigative approach. Professor Dahan highlights the paper's main findings including the emerging importance of CYP2D6 genetic polymorphisms and future directions for research.