Iron overload aggravates MDS pathophysiology; long-term outcomes after TPO-RA treatment in ITP; new insights into APL treatment outcomes by age and risk

In this week's episode we'll learn about the role of iron in myelodysplastic syndromes, or MDS. After that: long-term treatment outcomes in immune thrombocytopenia from the STOPAGO study.  Finally, new insights into APL treatment outcomes and prognostic factors from the large-scale Harmony APL project which used ATRA-Arsenic combination therapy.

Featured Articles:

• Genetic iron overload aggravates, and pharmacological iron restriction improves, MDS pathophysiology in a preclinical study
• Long-term follow-up of the STOPAGO study
• Acute promyelocytic leukemia: long-term outcomes from the HARMONY project