Core IM | Internal Medicine Podcast

#53 Heparin-Induced Thrombocytopenia: 5 Pearls Segment

48 min • 13 november 2019

 

Get CME Credit with ACP! Full Transcript with references and show notes Time Stamps

  • 4:30 What is the daily risk of thrombosis if HIT Is left untreated?
  • 5:40 What happens during platelet activation?
  • 07:11 How long does it take for patients to develop for IgG antibodies to Heparin to form?
  • 09:52 Is HIT common?
  • 10:28 Who is at higher risk for HIT?
  • 11:48 Why does low molecular weight heparin have a lower risk for HIT than unfractionated heparin?
  • 15:30 Approach to thrombocytopenia
  • 17:44 How do medications cause thrombocytopenia?
  • 18:38 With medications, what is the time course between medication initiation and thrombocytopenia?
  • 22:20 What is the sensitivity and specificity of anti-PF4 antibody?
  • 23:58 How does the serotonin-release assay (SRA) work?
  • 29:10 What type of anticoagulant do you choose for treating HIT?
  • 31:58 Why is it important to not use warfarin in patients with platelet counts <150,000?
  • 33:32 What is the treatment duration for a patient has confirmed HIT?
  • 36:29 Dr. Cuker’s story and the "Scarlet H"
  • 39:07 Dr. Linkin’s Recap
  • 42:25 Dr. Linkin’s story
  • 44:37 Pearl 5: Throwback to coronary calcium scores

 

 



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