Decoding Familial British Dementia

In this Dementia Researcher Podcast episode, Dr Aitana Sogorb Esteve hosts a discussion with Dr Charlie Arber and Sam Crawford from University College London, discussing their work on familial British dementia (FBD)

FBD is a rare form of dementia affecting only a handful of families. The discussion explores the latest findings from human stem cell models that are helping researchers understand FBD’s unique genetic and pathological features, and how that can inform a wider understanding of familial Alzheimer’s Disease.

Topics covered include:

Genetic causes and symptoms of familial British dementia
Use of stem cell models, particularly induced pluripotent stem cells (iPSCs), to study FBD in the lab
Potential biomarkers and implications for therapeutic research
How funding from the Race Against Dementia Ignition Fund is supporting advancements in rare dementia research

A transcript of this show, links and show notes and profile on all our guests are available on our website at https://www.dementiaresearcher.nihr.ac.uk.

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We gratefully acknowledge the support of our funders: Alzheimer’s Association, Race Against Dementia, Alzheimer’s Research UK, Alzheimer’s Society, and the National Institute for Health and Care Research.

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