Royal Wounds: Royal Bleed: Alexei Romanov, Hemophilia, and an Empire in Peril

In this episode of Diabetic Foot Files — Royal Wound Series, we examine Alexei Romanov's hemophilia B, tracing how an X‑linked clotting deficiency shaped his life and destabilized a dynasty.

We explain the clotting cascade failure that leaves fragile, delayed fibrin clots, why patients suffer deep joint and muscle bleeds, and what wounds hemophilia predisposes to.

Finally, we cover modern diagnosis and treatment — APTT, factor assays, factor replacement and non‑factor therapies — and practical rules for safely managing wounds and procedures in bleeding disorders.