When Metabolism Fails the Foot: Insulin Resistance, Hypertension & Non‑Healing Ulcers

In this episode of Diabetic Foot Files Dr. G traces diabetic foot ulcers upstream to metabolic causes: insulin resistance and chronic hyperinsulinemia drive sodium retention, sympathetic overactivity, RAS activation and endothelial dysfunction that produce microvascular collapse and poor wound healing.

Learn why clean-looking wounds still won’t close, how to target root causes (lifestyle, medications, supplements, and team-based care), and why limb salvage starts with restoring metabolism and vascular health—not just surface treatment.