Start / Docs Who Lift / Semaglutide vs tirzepatide are we closing the gap

Semaglutide vs. Tirzepatide: Are We Closing the Gap?

42 min • 24 juli 2025

How the STEP-UP trial came to life, and what made the 7.2mg dose possible

What the data actually says about weight loss and side effects at higher doses

Why trial design, pharmacokinetics, and estimands matter more than you think

What’s coming next in obesity meds: duals, triples, and even antagonists

The real talk on intermittent fasting, access issues, and preaching vs. science

Senaste avsnitt

Semaglutide for metabolic dysfunction associated steatotic liver disease (MASH).

2 maj | 22 min

Top 5 Women's Fitness Myths

25 april | 37 min

GLP-1 and metabolism and depression

11 april | 25 min

Do GLP-1 meds cause more fat cells?

19 mars | 26 min

Future of medicine - Direct Care

11 mars | 23 min

Tirzepatide and Muscle Loss with Dr. Grant Tinsley

28 februari | 28 min

The Super Bowl Hims and Hers Ad

17 februari | 25 min

NAD and NMN with Dr. Charles Brenner

12 februari | 39 min

The 60 Minutes Obesity Doctor - Dr. Fatima Cody Stanford

28 januari | 46 min

New Obesity Definition and Higher Wegovy Dose

20 januari | 29 min

The Ozempic Revolution - with Dr. Sowa

10 januari | 31 min

Microdosing GLP-1 and Cagrisema headlines

23 december 2024 | 40 min

Changing your workouts based on your menstrual cycle

18 december 2024 | 30 min

Zepbound vs Wegovy trial and compounded GLP-1s

9 december 2024 | 44 min

Types of Diabetes, CGMs, and More

25 november 2024 | 66 min

A new way of delivering healthcare - Direct Primary Care

20 november 2024 | 69 min

1st longer term tirzepatide study (3 years)

14 november 2024 | 45 min

Making America Healthy Again - Joe Rogan Podcast Review

1 november 2024 | 53 min

Cortisol 101

15 oktober 2024 | 31 min

New Healthcare Service

2 oktober 2024 | 22 min

Obesity medicine updates and Kardashian supplements

16 september 2024 | 40 min

Menopause 101

9 september 2024 | 76 min

Olympic controversies and GLP-1 for Alzheimer's and Heart Failure

7 augusti 2024 | 27 min

New Vitamin D Guidelines

30 juli 2024 | 31 min

Semaglutide and Blindness

8 juli 2024 | 51 min

Tirzepatide for Obstructive Sleep Apnea

26 juni 2024 | 20 min

Stomach Ablation for Weight Loss

21 juni 2024 | 34 min

FLOW trial and GLP-1 cost rant

4 juni 2024 | 46 min

South Park - The End of Obesity

28 maj 2024 | 21 min

Fallacies of Functional Medicine

16 maj 2024 | 27 min

Another response to Jillian Michaels and Bill Maher

30 april 2024 | 20 min

Bariatric surgery through the mouth? Endoscopy gastroplasty 101

24 april 2024 | 39 min

GLP-1 meds and Parkinson's and Heart Failure

12 april 2024 | 24 min

Lipedema Patient Journey

26 mars 2024 | 26 min

All about Lipedema - with Dr. Amron

13 mars 2024 | 52 min

GLP-1 Weight Loss Maintenance from Exercise

5 mars 2024 | 21 min

Bustin' Hyman Myths - GLP-1 edition

27 februari 2024 | 29 min

Does your doctor need to be in shape?

13 februari 2024 | 19 min

Docs Who Lift and Unbiased Science Crossover

31 januari 2024 | 76 min

The death of our supplement company and influencer pharma money

26 januari 2024 | 32 min

Pelvic Floor 101

10 januari 2024 | 24 min

How much protein should you eat? W/ Dr. Stu Phillips

19 december 2023 | 44 min

CGMs for those without type 2 diabetes w/ Dr. Nicola Guess

27 november 2023 | 47 min

SELECT results - Wegovy reduces heart attacks

17 november 2023 | 31 min

Zepbound - Tirzepatide for obesity approval

10 november 2023 | 23 min

Brain changes and obesity

24 oktober 2023 | 33 min

Tirzepatide updates from EASD

17 oktober 2023 | 38 min

Exercise for type 2 diabetes

3 oktober 2023 | 28 min

GLP-1 Agonists and Heart Health

29 augusti 2023 | 25 min

All about the Microbiome

11 augusti 2023 | 29 min

Eating Disorder Diaries

26 juli 2023 | 36 min

Diet Soda, Cancer, and the WHO

10 juli 2023 | 27 min

Internalized bias and what to do about it with Dr. Rebecca Pearl

21 juni 2023 | 36 min

Another genetic cause of obesity - Bardet Biedl Syndrome

8 juni 2023 | 56 min

The WHO and artificial sweeteners

31 maj 2023 | 31 min

Supplements for cholesterol and saunas for living longer

16 maj 2023 | 31 min

Chatting with the Obesity Medicine Association president

2 maj 2023 | 47 min

GLP-1 agonists and lean body mass loss part 2 w/ Dr. Grant Tinsley

24 april 2023 | 42 min

Food, exercise, and lifestyle as medicine?

19 april 2023 | 24 min

Intro to SGLT2 inhibitors - just pee out calories

3 april 2023 | 24 min

The myths of GLP-1 agonists

20 mars 2023 | 26 min

Obesity Medicine and Insurance Woes

13 mars 2023 | 34 min

Erythritol and Cardiovascular Disease

3 mars 2023 | 21 min

GLP-1s and Lean Mass Loss

27 februari 2023 | 25 min

Cholesterol Skeptics

21 februari 2023 | 34 min

Dubious Hormone Clinics and Batteries of Tests

13 februari 2023 | 38 min

Pediatric Obesity Guidelines Part Deux

6 februari 2023 | 31 min

Obesity Genetics and 60 Minutes

31 januari 2023 | 23 min

Red Flags of Quackery

23 januari 2023 | 44 min

Weight loss medicine and surgery for kids?

17 januari 2023 | 28 min

More Obesity Stigma - response to Steve Crowder

9 januari 2023 | 16 min

The harmful effects of anabolic steroids

2 januari 2023 | 49 min

Dietary Evangelicals

27 december 2022 | 33 min

Home Body Fat Scales - Grant Tinsley Interview

19 december 2022 | 43 min

Farm Babe Interview Part 2

12 december 2022 | 29 min

Farm Babe Interview part 1

6 december 2022 | 28 min

Lifestyle vs. Medicine

29 november 2022 | 20 min

GMOs, shelf-life, and more with Food Science Babe

21 november 2022 | 41 min

Pearls from Obesity Week

14 november 2022 | 28 min

Lifting weights - cradle to grave.

7 november 2022 | 27 min

Prediabetes and Type 2 Diabetes Medicines

1 november 2022 | 39 min

Hollywood weight loss drug abuse and new weight loss guidelines

24 oktober 2022 | 33 min

All about Diabetes

10 oktober 2022 | 36 min

What supplements should you take?

3 oktober 2022 | 43 min

Two Metabolic Case Studies

26 september 2022 | 39 min

Nutrition Studies and Media Headlines

19 september 2022 | 41 min

Neurobiology of Obesity with Dr. Stephan Guyenet

12 september 2022 | 55 min

Obesity causes low testosterone

5 september 2022 | 31 min

Intro to Osteoporosis

29 augusti 2022 | 28 min

Bariatric surgery for weight loss

22 augusti 2022 | 52 min

Response to Bill Maher

16 augusti 2022 | 38 min

The ultimate guide to hypothyroidism testing

8 augusti 2022 | 58 min

Hormones Demystified

1 augusti 2022 | 44 min

Tirzepatide...Bariatric surgery in an injection?

25 juli 2022 | 38 min

Do you have Low T?

18 juli 2022 | 35 min

Weight Loss Medicine: GLP-1s

11 juli 2022 | 44 min

Weight Loss Medicine: Phentermine, Qsymia, Contrave

4 juli 2022 | 45 min

Weight Loss Medicine: Orlistat and Plenity

27 juni 2022 | 27 min

Are you a fit for weight loss medicines?

20 juni 2022 | 31 min

Are your hormones stopping your weight loss?

13 juni 2022 | 43 min

Docs Who Lift Go Vegan

6 juni 2022 | 29 min

Weight Stigma

30 maj 2022 | 38 min

Do you need a continuous glucose monitor?

24 maj 2022 | 53 min

The Gym Clinic - Your Doctor's Office as a Gym

16 maj 2022 | 23 min

Nonalcoholic Fatty Liver Disease (NAFLD)

12 maj 2022 | 30 min

Intermittent Fasting and Weight Loss

2 maj 2022 | 28 min

Can you be healthy with obesity?

25 april 2022 | 24 min

Diet plans and accountability for weight loss - QnA Episode

18 april 2022 | 32 min

Medicines that cause weight gain

11 april 2022 | 31 min

How to Diagnose Obesity

4 april 2022 | 31 min

The Thyroid Diet

28 mars 2022 | 30 min

The Best Diet for Weight Loss

21 mars 2022 | 29 min

You don't have adrenal fatigue

14 mars 2022 | 28 min

Do Carbs Cause Obesity?

7 mars 2022 | 22 min

Artificial Sweeteners and Weight

27 februari 2022 | 23 min

Obesity as a disease

27 februari 2022 | 25 min

Who are the Docs Who Lift?

27 februari 2022 | 11 min

Semaglutide vs. Tirzepatide: Are We Closing the Gap?

Senaste avsnitt

CVS Pulled the Plug on Zepbound?!

More Than Weight Loss? GLP-1s and Cardiovascular Risk

Semaglutide vs. Tirzepatide: Are We Closing the Gap?

Clinical vs Anthropometric Obesity

GLP-1 meds and macular degeneration

Menopause, MHT, and GLP-1 medicines

The Science of Myostatin inhibitors, GLP-1 meds and Muscle Mass

Current State of Nutrition Research and MAHA

Joy Prescriptions

Zepbound versus Wegovy

Semaglutide for metabolic dysfunction associated steatotic liver disease (MASH).

Top 5 Women's Fitness Myths

GLP-1 and metabolism and depression

Do GLP-1 meds cause more fat cells?

Future of medicine - Direct Care

Tirzepatide and Muscle Loss with Dr. Grant Tinsley

The Super Bowl Hims and Hers Ad

NAD and NMN with Dr. Charles Brenner

The 60 Minutes Obesity Doctor - Dr. Fatima Cody Stanford

New Obesity Definition and Higher Wegovy Dose

The Ozempic Revolution - with Dr. Sowa

Microdosing GLP-1 and Cagrisema headlines

Changing your workouts based on your menstrual cycle

Zepbound vs Wegovy trial and compounded GLP-1s

Types of Diabetes, CGMs, and More

A new way of delivering healthcare - Direct Primary Care

1st longer term tirzepatide study (3 years)

Making America Healthy Again - Joe Rogan Podcast Review

Cortisol 101

New Healthcare Service

Obesity medicine updates and Kardashian supplements

Menopause 101

Olympic controversies and GLP-1 for Alzheimer's and Heart Failure

New Vitamin D Guidelines

Semaglutide and Blindness

Tirzepatide for Obstructive Sleep Apnea

Stomach Ablation for Weight Loss

FLOW trial and GLP-1 cost rant

South Park - The End of Obesity

Fallacies of Functional Medicine

Another response to Jillian Michaels and Bill Maher

Bariatric surgery through the mouth? Endoscopy gastroplasty 101

GLP-1 meds and Parkinson's and Heart Failure

Lipedema Patient Journey

All about Lipedema - with Dr. Amron

GLP-1 Weight Loss Maintenance from Exercise

Bustin' Hyman Myths - GLP-1 edition

Does your doctor need to be in shape?

Docs Who Lift and Unbiased Science Crossover

The death of our supplement company and influencer pharma money

Pelvic Floor 101

How much protein should you eat? W/ Dr. Stu Phillips

CGMs for those without type 2 diabetes w/ Dr. Nicola Guess

SELECT results - Wegovy reduces heart attacks

Zepbound - Tirzepatide for obesity approval

Brain changes and obesity

Tirzepatide updates from EASD

Exercise for type 2 diabetes

GLP-1 Agonists and Heart Health

All about the Microbiome

Eating Disorder Diaries

Diet Soda, Cancer, and the WHO

Internalized bias and what to do about it with Dr. Rebecca Pearl

Another genetic cause of obesity - Bardet Biedl Syndrome

The WHO and artificial sweeteners

Supplements for cholesterol and saunas for living longer

Chatting with the Obesity Medicine Association president

GLP-1 agonists and lean body mass loss part 2 w/ Dr. Grant Tinsley

Food, exercise, and lifestyle as medicine?

Intro to SGLT2 inhibitors - just pee out calories

The myths of GLP-1 agonists

Obesity Medicine and Insurance Woes

Erythritol and Cardiovascular Disease

GLP-1s and Lean Mass Loss

Cholesterol Skeptics

Dubious Hormone Clinics and Batteries of Tests

Pediatric Obesity Guidelines Part Deux

Obesity Genetics and 60 Minutes