Outpatient CAR T in Europe: Lessons from Barcelona

In this episode, Dr Alexandra Martínez Roca and Dr Beatriz Merchán Muñoz discuss how their team at Hospital Clínic de Barcelona has developed a fully outpatient programme for CAR T-cell therapy. They explain the evolution of their at-home programme, from outpatient transplantation and supportive care to outpatient CAR T administration, and describe the key clinical and logistical requirements for patient selection. The discussion explores caregiver training, monitoring for cytokine release syndrome and neurotoxicity, and the importance of dedicated multidisciplinary teams.  

The guests also share their experience with outpatient CAR T across academic and commercial products, highlighting safety outcomes, early discharge strategies, resource utilisation, and patient-centred benefits. They discuss practical considerations for centres interested in establishing similar programmes, including infrastructure, staffing, legislation, and continuous evaluation. Listen now for insights into the opportunities and challenges of delivering CAR T therapy beyond the hospital ward.  

This podcast episode is supported by Bristol Myers Squibb. 

Guests: Dr Alexandra Martínez Roca and Dr Beatriz Merchán Muñoz 

Affiliation: Hospital Clínic de Barcelona, Spain  

Host: Isabel Olivera-Martínez, PhD, EHA Medical Writer

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