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ESICM Talk
ESICM Talk

Drug Clearance in RRT: What Are the Determinants?

55 min•14 september 2026

Om avsnittet

How do you optimise drug dosing in a critically ill patient undergoing continuous renal replacement therapy (CRRT)? Drug dosing during CRRT can be challenging, with multiple factors influencing drug clearance and exposure.

In the latest ESICM Podcast, experienced clinical pharmacists explore the key determinants of drug clearance during CRRT, focusing on the interplay between the patient, the drug and the CRRT circuit.

The discussion highlights how drug characteristics, such as volume of distribution, and CRRT-related factors can influence drug removal and dosing, and why a personalised approach is essential to optimise treatment in critically ill patients.

Listen to the latest ESICM Podcast and discover what determines drug clearance during RRT.

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