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#002 Dr. George Brooks on Lactate Shuttle Theory, Relevance for Traumatic Brain Injury, and More

60 min • 2 december 2014

Dr. George A Brooks

Dr. George A Brooks, an expert in exercise physiology and lactate metabolism. Lactate, a once demonized molecule thought to form lactic acid and become a dead-end toxic metabolite, has been vindicated by the work of Dr. Brooks, his colleagues, and others.

In this episode, we discuss...

(00:00) Introduction
(01:40) Dr. Brooks’ experience as an athlete inspired his research on lactate
(06:50) Lactate and its relationship to muscle fatigue is misunderstood
(09:10) Adaptations to exercise improve mitochondrial functioning and lactate metabolism
(14:14) How to use lactate threshold training to improve performance
(23:49) Lactate improves brain health and cognitive function
(26:45) Lactate improves outcomes of traumatic brain injury via metabolism
(30:00) Lactate spares glucose, increasing antioxidants such as glutathione
(42:50) Early lactate administration following a traumatic brain injury is necessary, but challenging
(48:20) Lactate from exercise improves Parkinson's disease
(55:00) Brain metabolism following traumatic brain injury

If you’re interested in learning more, you can read the full show notes here.

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