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From Bench to Fireside

From Cancer’s Hidden Metabolic Tricks to Breakthrough Discoveries That Overcome Them with Roberta Zappasodi, PhD

40 min • 10 mars 2025

In this episode of From Bench to Fireside, host John Connolly, PhD, Chief Scientific Officer at the Parker Institute for Cancer Immunotherapy (PICI), interviews Roberta Zappasodi, PhD, Assistant Professor of Hematology and Medical Oncology and member of the PICI Center at Weill Cornell Medicine.

Dr. Zappasodi has been instrumental in uncovering immunotherapy resistance -- from her early career preparing vaccines from tumor samples, to her current, cutting-edge research on how tumor environments impact treatment. Together, they explore her discoveries on the relationship between tumor glycolytic states and vasculature, the importance of T-cell trafficking, and the transformative potential of combining therapies.

They also discuss the importance of moving immunotherapies to earlier treatment stages, PICI's role in fostering collaborative research, mentoring the next generation of researchers, her upcoming research on tumor metabolism... and more!

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From Bench to Fireside™ is a new podcast from the Parker Institute for Cancer Immunotherapy (PICI) that takes you from behind the lab bench to the frontiers of cancer research. Each episode features an interview with members of the PICI Network, pioneers in cancer immunotherapy and leaders at world-renowned cancer research institutions. Throughout the conversations, these experts weigh in on the potential of the human immune system to target and eradicate cancer cells, from the latest breakthroughs in immuno-oncology to their impact on patients. Along the way, they unpack the hurdles encountered and the opportunities that lie ahead.

Tune in to hear from scientific leaders who stand at the forefront of developing breakthrough immune therapies with the goal of turning all cancers into curable diseases. From Bench to Fireside™ is produced by the Parker Institute for Cancer Immunotherapy. Follow PICI on LinkedIn, X @parkerici or visit www.parkerici.org.

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