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From Concept to Medicine – A Comprehensive Drug Development Journey

167 - Precision Medicine & Genomic Innovations (S12E2)

10 min • 2 juni 2025

This episode explores advances in genomics and precision medicine that enable personalized therapies. Dialogue on genetic profiling, biomarkers, and tailored treatment approaches are presented with detailed literature examples. The conversation notes the foundation of personalized medicine starts with the human genome, our complete set of DNA instructions.

The conversation explores how, while we share something like 99% of our DNA, it's that tiny bit of variation that makes us unique and how variation influences our health, our risk for diseases, and how we respond to treatments. Discussions of cancer treatment shifts, pharmacokinetics, and the development of HIV protease inhibitors are also included. Technology and artificial intelligence are covered in detail.

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