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FYI – For Your Innovation

The Evolving World of RNA Editing with Dr. David Nelles

43 min • 8 november 2021

As the year comes to an end, we would like to thank everyone who listened to the FYI — For Your Innovation podcast. 2021 was another up and down year, as the world continues to battle the COVID-19 pandemic. In this final episode of 2021, we compiled some of our most interesting podcast episodes for you. Please enjoy this summary and tune back in when we return in 2022 with a new and improved version of FYI.

Key Points From This Episode:
  • Factors that caused CRISPR to dominate the gene editing space.
  • David explains the difference between DNA and RNA, using a football analogy.
  • The goal that David centered his PhD around.
  • Variety that exists amongst RND molecules.
  • Benefits of targeting RNA in diseased cells, rather than DNA.
  • Why RNA lagged behind DNA in terms of technological developments.
  • A theory about the role played by RNA in the past.
  • Methods of RNA editing.
  • Comparing homology directed repair (HDR) and non homologous end joining (NHEJ).
  • David provides a breakdown of the various different guides and enzymes.
  • Three kinds of vector systems, and how they work.
  • Examples of the types of RNAs that exist.
  • What David is excited about in the future of the RNA technology field.

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En liten tjänst av I'm With Friends. Finns även på engelska.

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