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HPMoR and the Limits of Rationality
HPMoR and the Limits of Rationality

Bogus Ep 1, pt 1: Good-genics

1 tim 57 min•20 oktober 2026

Om avsnittet

Elisa takes the wheel for a special episode exploring a concept popular in rationalist/effective altruist circles: "Genomic Emancipation," or, depending on who you ask, how and why you should have superbabies, as quickly and in as large numbers as possible.

Content warnings: eugenics, ableism, audism.


Citations, sources, and further reading

... are TOO LONG for this text box! Please check out the full reading list here: https://drive.proton.me/urls/AMNWHDKCSC#YZMyHHMYjDr6

Below is a selection of some of the major stuff because clicking links is hard, I get it.

Podcasts & video essays

Molly Conger, "Weird Little Guys": https://www.iheart.com/podcast/1119-weird-little-guys-201395214/ 

The Bell Curve - Shaun on YouTube: https://youtu.be/UBc7qBS1Ujo?si=SrLDOAq_o1BlPLfo 

Polygenic screening

Are "Designer Babies" a scam? Can You Really Choose Your 'Best' Baby?" (New York Magazine): https://archive.is/iN83l 

Creating Baby Geniuses to Thwart the AI Threat? (Yes, Really.) (Mother Jones): https://www.motherjones.com/politics/2026/04/gene-editing-optimization-thiel-altman-armstrong-andreessen-ai-iq/ 

Screening embryos for polygenic disease risk: a review of epidemiological, clinical, and ethical considerations: https://academic.oup.com/humupd/article/30/5/529/7684172 

Ethical and social implications of implementing polygenic embryo screening into clinical care: A scoping review https://www.sciencedirect.com/science/article/pii/S2949774426009155 

What a Polygenic Risk Score Can and Can’t Tell You:  https://magazine.hms.harvard.edu/articles/what-polygenic-risk-score-can-and-cant-tell-you .

These companies help parents try to pick their babies' traits. Experts are wary (NPR): https://www.npr.org/2026/05/06/nx-s1-5704317/genetic-embryo-screening 

Pronatalism

First Natalism Conference: https://www.politico.com/news/magazine/2024/04/28/natalism-conference-austin-00150338 

Simone wrote Trump's "mom medals" executive order: https://www.thehastingscenter.org/more-and-better-babies-the-dark-side-of-the-pronatalist-movement/ 

Pronatalist.org (Check out their Policy page!!)

Malcolm's LW post: https://www.lesswrong.com/posts/Ft9mpiX3RcisntrMN/malcolm-collins-s-shortform 

Talking about Aella: https://basedcamppodcast.substack.com/p/researching-a-gang-bang-made-my-wife

A sample of the Collins’ YouTube page: https://archive.org/details/screenshot-2026-10-12-183430 

Zvi’s interest in the population crisis, particularly re: the status of motherhood: https://www.lesswrong.com/posts/xJw5eetbzNNu9SiSZ/fertility-roundup-6-the-art-of-more-dakka   

Aella

A Faine Greenwood thread documenting various things about Aella, SlutCon, and the sex scene in the AI safety community in the Bay: https://bsky.app/profile/faineg.com/post/3mwjphbqsqs26 

Manifest

https://www.thenewcritic.com/p/manifest-man 

Tsvi

https://berkeleygenomics.org/ 

Chisme about Lighthaven's eugenics conference: https://undark.org/2026/04/08/genetics-artificial-inheritance/

"Genomic emancipation": https://berkeleygenomics.org/articles/Genomic_emancipation.html

"Genomic emancipation contra eugenics": https://berkeleygenomics.org/articles/Genomic_emancipation_contra_eugenics.html

IQ, genes, and environment

Is IQ Genetic? https://acisiq.com/is-iq-genetic-what-heritability-actually-means 

Ditch "g" factor: https://pmc.ncbi.nlm.nih.gov/articles/PMC10301777/ 

Penn State (2024): https://science.psu.edu/news/genes-or-environment-new-model-understanding-disease-risk-factors and (2025): https://www.nature.com/articles/s41591-024-03483-9 

Jonathan Anomaly

Source for Johnomaly's given name (and the picture of Cofnas, Yarvin, and Hanania): https://www.pinkerite.com/2025/03/jonathan-anomaly-files-slapp-lawsuit.html 

"Can 'eugenics' be defended?" https://link.springer.com/article/10.1007/s40592-021-00129-1 

"The Superbaby Factory" https://investigations.hopenothate.org.uk/superbaby-factory/ 

Disabilities!!!

Autistic Self Advocacy Network comments about germline editing: https://autisticadvocacy.org/2019/10/asan-comments-on-the-clinical-use-of-human-germline-genome-editing/ 

Parents do not regret their Down syndrome children! https://pmc.ncbi.nlm.nih.gov/articles/PMC3353148/ 

Iceland https://www.abc.net.au/news/2024-05-01/iceland-prenatal-testing-down-syndrome-ethics/103781058 

Both and! https://www.science.org/content/article/implants-can-help-deaf-kids-hear-many-still-struggle-spoken-language 

Film and culture recs

Sound and Fury (2000) + 2006 followup short - 

A World Without Down Syndrome (2016) - Actress and BBC presenter Sally Phillips bounces from NHS offices to British living rooms to Iceland, all to investigate what is motivating people to terminate Down pregnancies. Phillips has a child with Down syndrome.

Stuff I read for this episode but didn't get to

"The New Eugenics" (is IVF):https://pmc.ncbi.nlm.nih.gov/articles/PMC5965496/

Jonathan Anomaly smuggling more race science in: https://altrightorigins.com/2020/07/03/guest-post-on-the-intellectual-dishonestly-of-recent-hereditarian-papers-part-three/ 

Herasight goes all in on eugenics https://theinfinitesimal.substack.com/p/embryo-selection-company-herasight 

Stuff we mentioned

Jack Saint’s “Cultural Gen0c1d3”: https://youtu.be/dTfR4xjqeUM?si=fiYtvpYg79J9RPoq 

Australia’s history of cultural genocide in the Stolen Generations: https://australian.museum/learn/first-nations/stolen-generation/

OpenAI’s hack of Australia’s Medicare statistics portal (which Anthea mischaracterized as a hack into Medicare enrollment): https://arstechnica.com/ai/2026/09/heres-what-actually-happened-in-openais-australian-govt-server-hack/ 

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