Painkillers, Opioids, Heroin, Fentanyl, Oxycodone, NSAIDs, & Neuroscience of Pain | David Roberson | 52

Send us Fan Mail

Nick Jikomes talks to Dr. David Roberson, a neuroscientist and co-founder of three ongoing biotech companies: Nocion Therapeutics, Blue Therapeutics, and Blackbox Bio. David is an expert in the neuroscience of pain and the conversation focuses mainly on pain: how does our brain sense and perceive pain? Why does pain sometimes become chronic, and last for a long-time? How do various classes of pain drugs work to relieve pain? 

They discuss NSAIDs and opioids, including oxycodone, heroin, and fentanyl, as well as some interesting novel pain drugs currently in development. 

A portion of the podcast has a visual component, where David shows some of the technology he has helped develop that allows for automated, high-throughput measurements of animal behavior to detect and measure pain. Towards the end, they also discuss how this tech could be used for the characterization of novel psychoactive drugs and psychedelics. 

*Not medical advice.

Support the show

Health Products by M&M Partners:

• AquaTru: Water filtration devices that remove microplastics, metals, bacteria, and more from your drinking water. Through link, $100 off AquaTru Carafe, Classic & Under Sink Units; $300 off Freestanding models.
• OmegaQuant: At-home blood testing to see fatty acid profiles, including omega-3 fatty acids. Use link to see options and support M&M.
• SiPhox Health: Comprehensive, cost-effective bloodwork from the comfort of home. Use code TRIKOMES for 20% off.
• KetoCitra—Ketone body BHB + electrolytes formulated for kidney health. Use code MIND20 for 20% off any subscription (cancel anytime)
• SporesMD: Premium mushrooms products (gourmet mushrooms, nootropics, research). Use code 'nickjikomes' for 20% off.

For all the ways you can support my efforts