Start / Mind & Matter / Metabolic switching fasting ketosis neuroplasticity diet neurodegenerative disease mark mattson 139

Metabolic Switching, Fasting, Ketosis, Neuroplasticity, Diet & Neurodegenerative Disease | Mark Mattson | 139

101 min • 14 februari 2024

Send us a text

About the Guest: Mark Mattson, PhD is a semi-retired neuroscientist at Johns Hopkins who ran a research lab at the NIH for many years. He wrote the book, "The Intermittent Fasting Revolution."

Episode Summary: Nick and Dr. Mattson discuss: intermittent fasting & diet; ketosis & metabolic switching; aging & neurodegenerative disease; exercise, stress, and neuroplasticity; and more.

*This content is never meant to serve as medical advice.

Support the show

Affiliates:

Seed Oil Scout: Find restaurants with seed oil-free options, scan food products to see what they’re hiding, with this easy-to-use mobile app.
AquaTru: Reverse osmosis water filters. Remove metals, microbes, endocrine disruptors and toxins from drinking water. $100 off AquaTru filters through link.
KetoCitra—Ketone body BHB + electrolytes formulated for kidney health. Use code MIND20 for 20% off any subscription (cancel anytime)
Lumen device to optimize your metabolism for weight loss or athletic performance. Code MIND for 10% off
SiPhox Health—Affordable at-home blood testing. Key health markers, visualized & explained. Code TRIKOMES for a 20% discount.
MASA Chips—delicious tortilla chips made from organic corn & grass-fed beef tallow. No seed oils or artificial ingredients. Code MIND for 20% off

For all the ways you can support my efforts

Senaste avsnitt

Seed Oils & Heart Disease: Oxidized LDL, Cholesterol, Fat & Cardiology | Tucker Goodrich | 244

7 augusti | 99 min

Evolution & Variation in Human Diet, Energy Expenditure & Metabolism | Herman Pontzer | 243

1 augusti | 110 min

Sunlight: Cosmology, Energy Metabolism & the Physics of Life | Robert Fosbury | 242

27 juli | 133 min

Synapse Energetics & Fat Metabolism in the Brain | Timothy Ryan | 241

23 juli | 86 min

Microbiome as a Modifiable Organ System | Eugene Chang | 240

18 juli | 88 min

Metabolic Switching, Fasting, Ketosis, Neuroplasticity, Diet & Neurodegenerative Disease | Mark Mattson | 139

Senaste avsnitt

Seed Oils & Heart Disease: Oxidized LDL, Cholesterol, Fat & Cardiology | Tucker Goodrich | 244

Evolution & Variation in Human Diet, Energy Expenditure & Metabolism | Herman Pontzer | 243

Sunlight: Cosmology, Energy Metabolism & the Physics of Life | Robert Fosbury | 242

Synapse Energetics & Fat Metabolism in the Brain | Timothy Ryan | 241

Microbiome as a Modifiable Organ System | Eugene Chang | 240

Sleep Duration, Sleep Timing & Short-Sleepers | Ying-Hui Fu | 239

Hormones, Endocrine Disruptors & the Fate of Modern Liberal Society | Charles Cornish-Dale | 238

Circadian Biology: Genetics, Behavior, Metabolism, Light, Oxygen & Melatonin | Joseph Takahashi | 237

Cell Biology: Cytoskeleton, Self-Assembly & Self-Organization, Wound Healing | Bill Bement | 236

Computational Neuroscience, Machine Learning vs. Biological Learning, Large Language Models | Marius Pachitariu | 235

Brain Fat: Dietary PUFAs, Cannabinoids, Fatty Acid Binding Proteins, Anxiety & Mood | Steven Laviolette | 234

Feel the Burn: Seed Oils, Memes & Oxidative Stress | Brian Kerley | 233

SSRIs, Sexual Dysfunction, Suicide & Mass Shootings, How FDA Works | David Healy | 232

Psychedelic Chemistry, Magic Mushrooms, Kratom, Gray Market Research Chemicals, Vape Shops | Andrew Chadeayne | 231

Psilocybin & MDMA: Inflammation, Stress & Brain-Body Communication | Michael Wheeler | 230

Linoleic Acid, Seed Oils, mTOR & Breast Cancer | Nikos Koundouros & John Blenis | 229

Rhythms, Memory, Time, Place, Representation & the Brain | György Buzsáki | 228

Biophysics of Life: Biophotons, Light, Quantum Biology, Regeneration & Cancer | Nirosha Murugan | 227

Psychedelics & Cerebral Cortex: Neuroplasticity, Psilocybin, Ketamine | Alex Kwan | 226

Nutrition Epidemiology: Fake Science? | John Speakman | 225

Cancer Biology: Metabolism, Mitochondria & Energy | Thomas Seyfried | 224

Ketogenic Diet: Cholesterol, Plaque & Heart Heart | Matthew Budoff | 223

Genetics & Neurobiology of Obesity: Hypothalamus, Leptin, Gut Hormones, Weight Loss Drugs | Giles Yeo | 222

Regenerative Energy & the Light Inside You | Jack Kruse | M&M 221

Cell Death, Oxidative Stress, PUFAs & Antioxidants | Pamela Maher | 220

Shamanism, Human Culture & the Evolution of Religion | Manvir Singh | 219

Chemical Exposures, Neurodegenerative Disease & Exposomics | Gary Miller | 218

Communication & Social Cognition in Elephants & Animals | Mickey Pardo | 217

Can Aspirin Prevent Cancer Metastasis? | Rahul Roychoudhuri | 216

Cancer Metabolism: Sugar, Fructose, Lipids & Fasting | Gary Patti | 215

Gut Microbiome Plasticity | Peter Turnbaugh | 214

Causes of Diabetes: Insulin, Mitochondria, Genetics, Metabolism | Scott Soleimanpour | 213

How Science Works: Meta-Research, Publishing, Reproducibility, Peer Review, Funding | John Ioannidis | 212

Short-Chain Fatty Acids, Diabetes Subtypes & Wearable HealthTech | Michael Snyder | 211

Public Health & Trust in Science in the Post-COVID Era | Martin Kulldorff | 210

Thyroid Biology in Health & Aging | Diana van Heemst | 209

Glyphosate, Choline & Alzheimer's: Toxins & Nutrition to Prevent Neurodegeneration | Ramon Velazquez | 208

Glycosylation, CDGs & Role of Sugars Beyond Energy Production | Eva Morava | 207

Cultural Evolution, Religion & the Origins of WEIRD Psychology | Joseph Henrich | 206

Systems Biology, Personalized Medicine, AI & the Future of Health | Lee Hood | 205

Preventive Medicine, Personalized Nutrition & Changing Your Microbiome | Momo Vuyisich | 204

Metagenomics, Microbiome Transmission, Gut Microbiome in Health & Disease | Nicola Segata | 203

Why Do Animals Sleep? | Vlad Vyazovskiy | 202

Aroma, Olfaction & Using AI to Digitize Smell | Alex Wiltschko | 201

Dietary Fats & Seed Oils in Inflammation, Colon Cancer & Chronic Disease | Tim Yeatman & Ganesh Halade | 200

Ancient Diets, Human Carnivory, Mammoth Hunting, Clovis Culture & Origin of Native Americans | Ben Potter & Jim Chatters | 199

Vaccine Adverse Events & mRNA Biotechnology | Jessica Rose | 198

Creation Myths, Stoned Apes & the Eve Theory of Consciousness | Andrew Cutler

Neurobiology of Stress: Resilience, HPA Axis, Stress Hormones, Sex Differences, Early Life | Rosemary Bagot | 191

Mental Illness & Substance Abuse: Genetics, Psychosis, THC, Dopamine & the Brain | Jibran Khokhar | 190

Vaccine Contamination & Fiat Science | Kevin McKernan | 196

Skin Biology: Hormones, Light, Vitamin D, Melatonin & Stress | Andrzej Slominski | 189

Psychedelics, Functional Neuroimaging & the Human Brain | Joshua Siegel | 188

Synesthesia & Effects of Digital Technology on Brain & Mental Health | Richard Cytowic | 187

Kidney Biology: Simple Diet & Lifestyle Practices for Kidney Health | Thomas Weimbs | 186

Self-Experimentation (n=1) in Metabolic Health, Lipid-Energy, Trust in Medical Institutions | Nick Norwitz | 195

Sugar & Sweeteners: Are They Really Addictive or Unhealthy? | Nicole Avena | 185

Endocrine Disruptors & Metabolism: Microplastics, BPA, Estrogen, Insulin, Pancreas & Metabolic Dysfunction | Angel Nadal | 184

Calorie Restriction & Fasting: Aging, Immunity, Health Biomarkers, Stress, Genetics | Gary Churchill | 183

Neural Basis of Language in the Human Brain | Ev Fedorenko | 182

Neurosurgery, Blood-Brain Barrier, Ultrasound Technology for Brain Diseases & Disorders | Nir Lipsman | 181

Mother-Infant Bonding, Maternal Care & Breastfeeding, Neural Basis of Hunger & Social Behavior | Marcelo Dietrich | 180

Cave Art, Archaeology & the Emergence of Modern Humans | Maxime Aubert | 179

Ask Me Anything 1 | Nick Jikomes

Microbiome & Gut-Immune Interactions in Obesity & Metabolic Health | June Round | 178

Neural Basis of Pain, Placebo Effects, Opioid Pain Relief & Addiction | Gregory Scherrer | 177

Ancestral vs. Modern Human Diets, Seed Oils, Inflammation, Fat Oxidation, Influence of Industry on Food Science | Steven Rofrano | 194

Bad Science, Nutrition Epidemiology, History of Obesity Research, Diet & Metabolic Health | Gary Taubes | 176

Aging, Biological Clocks, Proteomics, Longevity & Healthspan | Austin Argentieri | 175

Adipose Tissue & Body Fat: Obesity, Insulin, Leptin, Fertility, Weight Loss & GLP-1 Drugs | Sean Hartig | 174

Psychedelics, Consciousness, Mental Health & the Entropic Brain | Robin Carhart-Harris | 173

Immune System, Gut Microbiome, Vitamin D, Cancer, Innate Immunity, Inflammation & Gut-Immune Interactions | Caetano Reis e Sousa | 172

Comparative Brain Evolution: Mammals, Primates & Humans | Robert Barton | 171

Sex Differences, Drugs & the Brain: Psychedelics, Psilocybin, Alcohol & Nicotine | Melissa Herman | 170

Epigenetics, Chromatin Plasticity & the Neural Basis of Memory | Giulia Santoni | 169

Sleep: Neural Circuits, Orexin/Hypocretin, Hypothalamus, Neuromodulators, Stress & Cortisol, Sleep Drugs & Ultrasound Technology | Luis de Lecea | 168

Plant Chemistry & the Chemical Basis of Marijuana Aroma | Iain Oswald | 167

History of Diet & Food, Population Size & Social Stability, Psychological Pandemics, Physical & Mental Health in Civilization Cycles | Rudyard Lynch | 193