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Molecular Modelling and Drug Discovery
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Bayesian Modelling of Synergistic Drug Combination Effects in Cancer Using Gaussian Processes - Leiv Rønneberg

50 min•7 juli 2022

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Abstract: High-throughput drug sensitivity experiments in cancer enable rapid in-vitro testing of various compounds on cancer cell lines, or patient-derived material, in order to determine the efficacy of a certain treatment. Accurate prediction of dose-response functions from a limited set of pre-clinical experiments is key to explore the large space of possible treatment options, or to prioritize which experiments to perform. This is particularly important when predicting the effect of drug combinations, where it is unfeasible to test all possible combinations...

Speakers: Leiv Rønneberg - https://twitter.com/ltronneberg 

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