Episode 104: The Genesis Mission, AI-Driven Science, & America's Race to Innovate

For decades, the path from scientific breakthrough to real-world impact has taken ten to twenty years, with researchers relying on tools not far removed from a high school chemistry lab. The Department of Energy's Genesis Mission aims to change that, harnessing artificial intelligence to compress discovery from decades to mere years. In this episode, we ask: Can a "Manhattan Project 2.0" for science deliver the breakthroughs America needs to stay ahead of China? 

Angela Sheffield joins NatSec Tech live at the 2026 AI+ Expo to share her perspective on AI's power to revitalize American science. Angela is the Director of AI Strategy for Energy at Accenture Federal Services, one of the private partners building the digital infrastructure behind the Genesis Mission. Drawing on her experience as a national lab scientist, military officer, and DOE program manager, she explains how connecting data across the national laboratories could unlock everything from critical mineral independence to next-generation nuclear reactors — and why the mission's aggressive deadlines signal a new era for American scientific ambition.

NatSec Tech is a product of the Special Competitive Studies Project.