1137-CTDPathSim2.0: Mapping of Cell Lines to Patient Tumors

This study introduces CTDPathSim2.0, a computational framework designed to identify which laboratory cell lines most accurately represent individual patient tumors. Researchers developed this tool because cell lines often undergo genetic changes in vitro, causing them to deviate from the biology of actual human cancers. By integrating multi-omics data—including gene expression, DNA methylation, an...去小宇宙查看完整单集简介
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