[2] UNA CÉLULA (cancerosa) RENEGADA. #OskarMarín-Bejar

TEMAS: - La entrada en el sistema científico - La importancia de reclutar a la gente adecuada - Las células cancerígenas que se esconden - Melanoma, cáncer de piel y lunares sospechosos - La importancia de la genética en el melanoma - “Salir al monte” en el País Vasco - Montañas del Pirineo - Los ARN no codificantes y microRNAs - Darwin y Lamarck en la ventaja de las células cancerígenas - Modelos ortotópicos de ratón: tumores humanos dentro de ratones - Vivir en Gante, Bélgica - Ciclismo: Lieja-Bastogne-Lieja y Alejandro Valverde - El campo de Single Cell Sequencing - A la suerte hay que acorralarla - John Rinn y Moreno-Matéos - El "Oscar Marín" que está en Londres NOTAS: Picos de más de 3000 metros recomendados en Pirineos: El Poset (3369m) y El Bachimala (3177m) Paso de “La canal Fonda” de El Poset. 212 picos de 3000 metros en el Pirineo https://viajaresdescubrir.com/ascension-posets/ https://www.acampamos.com/pico-de-bachimala/ One Renegade Cell https://www.goodreads.com/en/book/show/714346 LOCALIZACIÓN: Hotel Hesperia, Hospitalet de Llobregat Disculpas por la calidad del audio. Nos vinimos arriba grabando en una cafetería y el ruido de fondo era más del deseado. Estamos aprendiendo. SOBRE OSKAR MARIN BEJAR (info extraida de Linkedin): I obtained my Ph.D. in July 2015, trained as a RNA biologist focused in the understanding of the on-coding genome under the supervision of Dr. Maite Huarte, expert in chromatin regulation and RNA biology. Through my Ph.D., I published 2 studies as a first or co-first author in well-recognised journals in the genome biology field, I also contributed to several collaborations resulting in 4 publications (Nature Communication, Molecular cell, Journal of Cell Biology and Neurooncology). Meanwhile, I applied for postdoctoral fellowships to join the lab of an internationally recognised expert in non-coding RNAs and cancer biology, Dr. Chris Marine (Center of Cancer Biology VIB/KUL). I got a highly competitive fellowship (Incoming FWO-Pegasus2) cofounded by MSCA program to explore melanoma intratumor heterogeneity using single cell technologies. During this process, I have been able to establish a scientific network of outstanding researchers and medical oncologists from Massachusetts General Hospital, University of Zürich, UZ Leuven and many others. I published a first-author paper in Cancer Cell journal, honoured with a comment by Professor Grant McArthur (PeterMac, Melbourne), a world-leading physician in the field of targeted therapeutics and personalised medicine and a second-authorship in wide- interest journal, Cell. I also contributed to several collaborations resulting in 4 publications (Nature, two EMBO Molecular Medicine and Genome research). Throughout these years, I have also supervised 8 research projects carried out by 1 PhD student, 4 MsC students and 3 undergraduate students. Remarkably, all the master student under my supervision are doing the PhD in renown laboratories with their own PhD fellowships (FWO, BIF and FWO-SB). Now, I am a MSCA senior postdoc at IDIBELL (Barcelona) where I lead the ‘single cell GATA2 track’ research project. I currently aim to understand the contributions of the oncogenic addiction and the epigenetic regulation during the GATA2. I am particularly interested in how transcriptional rewiring is occurring during MDS/AML transition to identify cancer cell vulnerabilities for future precision medicine approaches. Since I started my career, I have been independently funded, including prestigious postdoctoral fellowships as I mentioned before. Additionally, I recently got the European Hematology Association Kick-off Grant, to support early career researchers, which will allow me to test a high-risk but potentially high impact idea to generate preliminary data, providing preliminary data to develop my own research.