Featuring a slide presentation and related discussion from Prof Peter Schmid, including the following topics:
- Evolution of the therapeutic landscape for metastatic triple-negative breast cancer; age of immunotherapy (0:00)
- Case: A woman in her early 40s with no actionable mutations (7:29)
- Evolution of antibody-drug conjugates (ADCs) in the management of metastatic breast cancer (11:13)
- TROP2-directed ADCs (15:22)
- Case: A woman in her early 50s with PD-L1-negative, HR-negative, HER2-low de novo metastatic breast cancer (20:21)
- Novel strategies utilizing approved and investigational ADCs (23:28)
- Case: A woman in her early 60s with loss of HER2 expression on disease progression (31:39)
- ADCs in combination with immunotherapy (32:51)
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