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Research To Practice | Oncology Videos

Myelofibrosis — An Interview with Dr Raajit K Rampal on Key Presentations from the 66th American Society of Hematology (ASH) Annual Meeting (Companion Faculty Lecture)

31 min16 april 2025

Featuring a slide presentation and related discussion from Dr Raajit K Rampal, including the following topics:

  • Overview of the current JAK inhibitor landscape (0:00)
  • Factors predicting clinical benefit in patients with myelofibrosis (MF) receiving ruxolitinib (3:02)
  • Clinical data supporting the use of fedratinib after prior ruxolitinib for MF (9:17)
  • Emerging clinical findings on pelabresib in combination with ruxolitinib for previously untreated MF (12:13)
  • Available clinical data with novel BET inhibitors (15:00)
  • Utility of selinexor in combination with ruxolitinib for MF previously treated with ruxolitinib (16:50)
  • Emerging efficacy and safety findings reported with imetelstat for MF (18:57)
  • Clinical findings reported with the MDM2 inhibitor navtemadlin for MF (21:15)
  • Available clinical data with the TGF-beta inhibitor elritercept for MF (24:05)
  • Other novel agents and strategies under investigation for MF (26:06)

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