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Research To Practice | Oncology Videos
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Non-Hodgkin Lymphoma | Oncology Today with Dr Neil Love: Bispecific Antibodies in the Management of Non-Hodgkin Lymphoma with Dr Matthew Matasar

46 min•12 oktober 2023

Featuring an interview with Dr Matthew Matasar, including the following topics:

  • Rationale for the evaluation of anti-CD20 x CD3 bispecific antibodies in the treatment of non-Hodgkin lymphoma (NHL) (0:00)
  • Incidence, severity and time course of cytokine release syndrome, neurotoxicity/ICANS and other adverse events associated with bispecific antibodies; recommended mitigation and management protocols (4:39)
  • Activity of and similarities and differences among the various bispecific antibodies for NHL (12:20)
  • Eligibility, efficacy and durability of response with mosunetuzumab, glofitamab, epcoritamab and odronextamab; ongoing and planned evaluations of bispecific antibodies alone and in combination with other systemic therapies (19:18)
  • Optimal integration of bispecific antibody platforms into treatment algorithms for patients with NHL (32:12)
  • Emerging results with bispecific antibodies for mantle cell lymphoma and chronic lymphocytic leukemia (41:51)

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