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Research To Practice | Oncology Videos

Squamous Cell Carcinoma of the Anal Canal — An Interview with Dr Marwan Fakih

37 min12 februari 2026

Featuring an interview with Dr Marwan Fakih, including the following topics:

  • Etiology and incidence of squamous cell carcinoma of the anal canal (SCAC) (0:00)
  • Novel therapeutic strategies for the treatment of SCAC: Immunotherapy combinations and monitoring for recurrence with circulating tumor DNA assessment (4:37)
  • Perspectives on the overall survival benefit observed with first-line retifanlimab and carboplatin/paclitaxel; potential for cure for patients with SCAC (8:22)
  • Case: A woman in her mid 60s with recurrent unresectable metastatic SCAC receives retifanlimab with carboplatin/paclitaxel (16:56)
  • Case: A woman in her mid 60s with recurrent unresectable metastatic SCAC receives single-agent immunotherapy (25:22)
  • Case: A woman in her 60s with previously untreated metastatic SCAC receives chemotherapy and attains a complete response (29:21)
  • Future directions for the treatment of SCAC (33:22)

CME information and select publications

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