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Research To Practice | Oncology Videos

Squamous Cell Carcinoma of the Anal Canal — An Interview with Dr Marwan Fakih (Companion Faculty Lecture)

37 min11 februari 2026

Featuring a slide presentation and related discussion from Dr Marwan Fakih, including the following topics:

  • Overview of etiology, incidence and staging of squamous cell cancer of the anal canal (SCAC) (0:00)
  • Systemic therapy approaches to the management of recurrent unresectable and metastatic SCAC (6:17)
  • Available data with anti-PD-1 (pembrolizumab, nivolumab, retifanlimab) and anti-CTLA-4 (ipilimumab) agents in the management of unresectable metastatic SCAC previously treated with chemotherapy (12:59)
  • Immunotherapy combined with chemotherapy for the front-line treatment of SCAC (20:48)
  • Efficacy and safety of retifanlimab combined with carboplatin/paclitaxel as first-line treatment for SCAC in the Phase III POD1UM-303 trial (23:43)

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