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Science Friday

How Do GLP-1 Drugs Override Our Biology?

19 min8 juli 2025

GLP-1 medications like Ozempic have dominated headlines over the past couple of years. When writing his new book, Diet, Drugs and Dopamine: The New Science of Achieving a Healthy Weight, former FDA commissioner David Kessler wanted to unpack the science beyond those headlines. He also has a personal relationship with the subject, having taken GLP-1 medications himself. Host Flora Lichtman joins Kessler to talk about the latest science on metabolism, weight loss, and how these blockbuster drugs actually work.

Guest: 
Dr. David Kessler is the former commissioner of the FDA and the author of Diet, Drugs and Dopamine: The New Science of Achieving a Healthy Weight.

Transcripts for each episode are available within 1-3 days at sciencefriday.com.

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