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This Fortnight in Medicine XII

41 min•5 november 2025

Effects of Intensive Blood Pressure Control in Patients With Frailty: A Post Hoc Analysis From ESPRIT

* Lowering systolic blood pressure to less than 120 mm Hg versus less than 140 mm Hg in patients with high cardiovascular risk with and without diabetes or previous stroke: an open-label, blinded-outcome, randomised trial

* Reduction of Antihypertensive Treatment in Nursing Home Residents

Polysaccharide Conjugate Vaccine against Pneumococcal Pneumonia in Adults

* A trial to evaluate the safety and immunogenicity of a 20-valent pneumococcal conjugate vaccine in populations of adults ≥65 years of age with different prior pneumococcal vaccination



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