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Sensible Medicine

This Fortnight in Medicine VI

35 min • 13 augusti 2025

A “manel” reviewing trials and studies that explore the benefits and harms of hormone replacement therapy.

The Women’s Health Initiative

* Risks and benefits of estrogen plus progestin in healthy postmenopausal women: principal results from the Women's Health Initiative randomized controlled trial

* The Women's Health Initiative Randomized Trials and Clinical Practice: A Review

* The Women’s Health Initiative Hormone Therapy Trials: Update and Overview of Health Outcomes During the Intervention and Post-Stopping Phases

Meta-analysese

* A systematic review and meta-regression analysis to examine the ‘timing hypothesis’ of hormone replacement therapy on mortality, coronary heart disease, and stroke

* Mortality Associated with Hormone Replacement Therapy in

Younger and Older Women

History: Observational HRT Data

* Postmenopausal estrogen and progestin use and the risk of cardiovascular disease

* Hormone therapy to prevent disease and prolong life in postmenopausal women

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Senaste avsnitt

This Fortnight in Medicine VI

13 augusti | 35 min

This Fortnight in Medicine V

30 juli | 33 min

This Fortnight in Medicine (IV)

16 juli | 36 min

Friday Reflection 49: The Patients of 12 Reisman

11 juli | 11 min

This Fortnight in Medicine (Episode III)

2 juli | 40 min

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