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The Biotech Startups Podcast
The Biotech Startups Podcast

If It's Getting More Complex, You're Going the Wrong Way | Scott Chetham (4/4)

41 min•22 oktober 2026

Om avsnittet

Excedr provides research labs with equipment leases on founder-friendly terms to support paths to exceptional outcomes. Learn more at https://www.excedr.com/partners.

“If things are getting more complex, you're going in the wrong direction.”

Scott Chetham explains why he left Google and Verily to tackle the unglamorous planning work that slows clinical development. He recounts sketching the company in Costa Rica, raising a pre-napkin-stage round with Polaris, finding an early customer, and adapting when COVID-19 disrupted pharma economics.
He also traces Faro's evolution from a scenario-planning calculator into a broader platform for protocol review, data transformation, automation, and research support. The conversation covers regulated AI, the limits of historical data and trial simulation, customer trust, founder stamina, enterprise transformation, and the shift from pushing a market to being pulled by it. Scott closes with the advice that has stayed with him: fight complexity everywhere.

Key Topics Covered:
  • Leaving Google and Verily to solve clinical development's planning bottleneck
  • Building a company from a Costa Rica planning retreat
  • Raising a pre-napkin-stage venture round with Polaris
  • Finding early customers during COVID-19 disruption
  • The realities of second-time founding and balancing family life
  • Referral-driven enterprise sales in a trust-sensitive industry
  • Faro's evolution from a clinical trial cost calculator to an automation platform
  • Knowledge graphs, data transformation, and constrained LLM workflows
  • Automating protocol review and electronic data capture programming
  • Why pre-2019 clinical data may mislead modern trial design
  • The limits of replacing clinical trials with simulations
  • Transforming large pharma organizations under pressure
  • Moving from pushing automation to responding to customer demand
  • Founder leverage, sustainable pace, and organizational scale
  • Why increasing complexity is a warning sign

If you enjoy The Biotech Startups Podcast, please consider subscribing, leaving a review, or sharing it with your friends. Thanks for listening.

Listen and subscribe to The Biotech Startups Podcast:
Apple Podcasts: https://podcasts.apple.com/us/podcast/the-biotech-startups-podcast/id1679591994
Spotify: https://open.spotify.com/show/2PSL162R2s0zOwU5913Zv4
TBSP YouTube: https://www.youtube.com/@thebiotechstartupspodcast
TBSP website: https://www.thebiotechstartupspodcast.com/?utm_source=podcast&utm_medium=show-notes&utm_campaign=the-biotech-startups-podcast-ep287

Find our guest, Scott Chetham, at these links:
LinkedIn: https://www.linkedin.com/in/scott-chetham-2949001
Website: https://farohealth.com/

Find our host, Jon Chee, at these links:
LinkedIn: https://www.linkedin.com/in/jonchee/

Learn more about Excedr:
LinkedIn: https://www.linkedin.com/company/excedr/
Website: https://www.excedr.com

Intro & Outro Songs Created by OkKyojin:
https://flow.page/kyojin

Resources & Articles:
Faro Health: https://farohealth.com/
Polaris: https://www.polaris.vc/
Verily: https://verily.com/
Anthropic: https://www.anthropic.com/
ClinicalTrials.gov: https://clinicaltrials.gov/

Companies, Universities, & People Mentioned:
Google: https://www.google.com/
Verily: https://verily.com/
Polaris: https://www.polaris.vc/
Anthropic: https://www.anthropic.com/
Merck: https://www.merck.com/
Meta: https://about.meta.com/

Timestamps:
00:00 Intro
01:44 Leaving Google and Verily
02:50 A Company Sketched in Costa Rica
03:28 COVID Disrupts the Early Market
04:39 The Older Founder Advantage
05:44 Trust, Referrals, and Scaling
10:21 From Fancy Calculator to Platform
12:52 Regulated AI Needs Guardrails
14:45 Why the Ecosystem Must Work Together
17:29 When More Data Makes Things Worse
18:44 The Limits of Trial Simulation
24:40 Transforming Pharma Before Costs Break It
27:30 From Pushing to Being Pulled
37:20 Fight Complexity Everywhere
39:16 Outro


The Biotech Startups Podcast gives you a front-row seat to the business and science of building a biotech. Hosted by Jon Chee, CEO of Excedr, the show features honest conversations with founders, execs, and investors about their work, their companies, and how they got there. From scientific breakthroughs to startup lessons, each episode explores what it really takes to grow a life science company—from pre-seed to IPO.

The Biotech Startups Podcast med Excedr finns tillgänglig på flera plattformar. Informationen på denna sida kommer från offentliga podd-flöden.