Reboot #167 LIVE! CBC Abnormalities

Enjoy this Curbsiders classic and stay tuned this Wednesday, August 25, 2021 for a brand new CBC Abnormalities Triple Distilled episode.
Take a deep dive into common CBC abnormalities. We recorded LIVE at joint grand rounds between Walter Reed NMMC and Uniformed Services University with hematologist, Dr. Mary Kwok MD. Topics include: which parts of the complete blood count (CBC) are most important, interpreting the differential, when to order flow cytometry, who needs a hematology consult and simplified approaches to patients with leukocytosis, leukopenia, erythrocytosis and thrombocytopenia.
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Credits

• Written, Produced and Edited by: Matthew Watto MD, FACP
• Cover Art and Infographic by: Matthew Watto MD, FACP
• Hosts: Stuart Brigham MD; Matthew Watto MD, FACP; Paul Williams MD, FACP
• Guest: Mary Kwok MD

Sponsor: American College of Physicians acponline.org/100curb ACP CME 100 virtual video package includes 75 hours of practice-changing updates by expert faculty from Internal Medicine Meeting 2021 acponline.org/100CURB. Plus enjoy an exclusive: 25 bonus CME sessions and access until June 1, 2024!

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Time Stamps* Time Stamps refer to ad-free version

• 00:00 Intro; Paul shame’s the audience; Guest bio
• 03:17 Guest one-liner, book recommendation* –Emperor of All Maladies (book) by Siddhartha Mukherjee, When Breath Becomes Air (book) by Paul Kalanithi; Career advice -set goals for whatever you’re learning.
• 08:43 Picks of the week: John Wick 3 (film); The Movies That Made Me (podcast) by Joe Dante; The Tim Ferriss Podcast with Julie Rice of Soul Cycle; Infinity Chamber (film) by Travis Milloy
• 11:50 A case of asymptomatic leukocytosis; Red flags; Repeat the CBC until it’s normal
• 17:30 The peripheral smear; Leukemoid reaction
• 20:00 The physical exam; When to send flow cytometry?
• 22:18 A case of lymphopenia; benign ethnic neutropenia; What to look for in the history
• 27:10 A case of erythrocytosis; Checking EPO levels; JAK2 mutation; Differential Diagnosis; Therapeutic Phlebotomy; Physical findings of Polycythemia Vera
• 36:53 A case of thrombocytopenia; Lab workup; Differential diagnosis; Pathophysiology; Culprit meds
• 45:35 Advice for internists
• 46:36 Take Home Points
• 47:46 Dr. Kwok’s disclaimer
• 48:10 Outro and post credit scene