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The Dr Louise Newson Podcast

66 – PMDD and mental health: what’s really going on?

31 min14 maj 2026

What if severe changes in your mental health were being driven by your hormones?

In this episode, Dr Louise Newson is joined by Dr Isabella Sillar, an Australian doctor, who shares her powerful and deeply personal experience of living with premenstrual dysphoric disorder (PMDD). Despite being in medical training, Isabella struggled for years with severe symptoms including suicidal thoughts, repeated misdiagnoses and treatments that failed to address the underlying cause.  

They explore how hormonal fluctuations can influence mental health, why PMDD is so often misunderstood and the consequences of treating symptoms without considering hormones. Isabella also shares how finding the right treatment transformed her life, and how her experience has shaped the way she now supports her own patients.

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