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The Drug Discovery World Podcast

Nano Insights: Unveiling the Role of mRNA Analytics in cGMP Manufacturing with Lonza and beyond

15 min20 februari 2025

In this podcast we speak to experts from Lonza and Oxford Nanopore about their collaboration to bring direct mRNA sequencing (including N1-Methyl-pseudouridine) to a regulated environment and establish the new gold standard in sequencing technology.

We discuss how nanopore sequencing will be used to perform unbiased identity testing while enabling the simultaneous analyses of multiple critical quality attributes such as integrity (mRNA length and poly-A tail length) and capping.

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