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The Genetics Podcast

EP 177: The vision of Our Future Health with Raghib Ali

43 min6 mars 2025

This week on The Genetics Podcast, Patrick is joined by Raghib Ali, CEO, CMO, and Principal Investigator of Our Future Health UK. As a clinical epidemiologist with a passion for reducing health inequalities, Raghib offers fresh insights into the priorities, challenges, and transformative impact of the groundbreaking genomics initiative, Our Future Health. 

Show Notes: 

0:00 Intro to The Genetics Podcast

01:00 Welcome to Raghib and background on Our Future Health (OFH)

03:57 Diseases that are a priority for OFH or are likely to benefit from its impact

06:07 Challenges and opportunities for implementing change in the National Health Service (NHS), a partner of OFH, based on study findings

09:20 Factors that contributed to the rapid recruitment of participants to OFH

14:12 Efforts to ensure diversity of OFH participants and facilitate accessibility for all

16:35 Why OFH chose to use arrays for genomic profiling

18:57 Navigating the obstacles and opportunities in public and private partners

22:28 Strengths and weaknesses of the medical record system in the UK

 

25:54 Efforts to rapidly provide results from OFH and integrating other datasets and techniques in the future

28:43 Raghib’s unique educational and training journey 

31:49 The importance of evaluating components beyond genetics for a full picture of health

33:28 Aims and findings of the first prospective cohort study in the UAE

35:26 The potential contribution of epigenetic inheritance to disease risk 

37:43 How Raghib overcame adversity early in life

40:56 Closing remarks 

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