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The Hematologist

No Scientific Link Found Between Sickle Cell Trait and Sudden Death

21 min • 28 april 2025

In this episode, Contributing Editor Samuel Wilson, MD, MSCR, an assistant professor of hematology at the University of North Carolina at Chapel Hill, talks with Michael DeBaun, MD, MPH, a professor of pediatrics and medicine at Vanderbilt University Medical Center and founder and director of the Vanderbilt-Meharry Sickle Cell Disease Center of Excellence. They talk about a systematic literature review, led by Dr. DeBaun and published in the journal Blood, that found no link between sickle cell trait and sudden death – a finding that challenges a long-standing myth about the trait. Support for this episode provide by Siemens Healthineers.

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