Ep. 108: “The Intestinal Epithelium” Featuring Dr. Mahima Swamy

Guest:

Dr. Mahima Swamy is a Program Leader at the University of Dundee, where her lab studies immune homeostasis in the intestinal epithelium. She talks about intestinal intraepithelial lymphocytes and the role of LRRK2 in Parkinson’s and Crohn’s disease.

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The Immunology Science Round Up

Fungal Meningitis in Mammals – Researchers examined Cryptococcus neoformans phenotypes and identified factors that drive mammalian virulence.

γδ T cell Receptor Activation – Using cryoelectron microscopy, researchers identified an MHC-independent antigen presentation mechanism distinct from αβ T cells.

Fungal Pulmonary Fibrosis – The Dectin-1-Raf1 axis is a key regulator of pulmonary fibrosis and a promising therapeutic target for fibrotic diseases.

Early-Life Fructose Exposure – High-fructose treatment of mouse and human microglia suppresses phagocytosis capacity.