Ep. 13: “Pathogens, Autoantigens, and Antigens” Featuring Dr. Frances Lund

Guest:

Dr. Frances Lund is the Charles H. McCauley Professor and Chair of the Department of Microbiology at the University of Alabama at Birmingham. Her lab showed that B cells not only make antibodies, but also produce cytokines that modulate the microenvironment. She currently studies the many roles of B cells, how to target B cells gone bad, and nasal vaccines for respiratory illnesses.

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The Immunology Science Round Up

A COVID-19 Vaccine Targeting CD40 – Researchers fused a CD40 monoclonal antibody to a SARS-CoV-2 protein, which stimulated dendritic cells and boosted the immune response of monkeys already exposed to the virus.

A T Cell Cancer Vaccine – Scientists generated a therapeutic cancer vaccine by genetically modifying T cells to deliver antigens and adjuvant signals to lymphoid tissues.

Dendritic Cells in Intestinal Immunity –  Intestinal dendritic cells have local specializations that depend on the microenvironment.

Stress and the Immune System – Psychological stress primes monocytes to an inflammatory state.

Image courtesy of Dr. Frances Lund