Ep. 24: “Autoimmune Disease” Featuring Dr. Jennifer Gommerman

Guest:

Dr. Jennifer Gommerman is a Professor of Immunology at the University of Toronto. Her team has uncovered a novel gut-brain axis that regulates neuroinflammation and is examining the role of B lymphocytes in Multiple Sclerosis (MS) patients and in animal models of MS. More recently, she has been studying the antibody response to SARS-CoV-2 in saliva samples from patients with COVID-19.

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The Immunology Science Round Up

Neutralizing Antibody Responses to Omicron – SARS-CoV-2-specific immunity wanes over time after two mRNA vaccine doses.

Determining T Cell Fate – Researchers identified T cell antigen receptor sequence features that promote regulatory T cell fate.

Fungi in the Gut – Mucosa-associated fungi protect mice against intestinal injury and infection via interleukin-22-dependent mechanisms.

T Cells in Glioblastomas – T cell dysfunction in the glioblastoma microenvironment is mediated by myeloid cells releasing interleukin-10.

Image courtesy of Dr. Jennifer Gommerman