Ep. 68: “Blood Transfusions” Featuring Dr. David Gibb

Guest:

Dr. David Gibb is an Assistant Professor at Cedars-Sinai Medical Center. His lab investigates inflammatory mechanisms in patients with sickle cell disease and lupus, focusing on mechanisms regulating immune responses to red blood cell antigens following transfusion.

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The Immunology Round Up

Regulation of Lymphoid Cells – NOD1 functions in murine hematopoietic cells as a major regulator of both the generation and differentiation of lymphoid progenitors.

The Aging Immune System – Type 2 memory CD4+ and CD8+ T cells increase with age and can produce more IL-4.

Microglia in Cancer Metastasis – Microglia play a distinct pro-inflammatory and tumor-suppressive role in breast cancer brain metastasis.

MAIT Cells in Mice and Humans – Environment influences MAIT cell development and function.