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The Most Interesting Thing in AI

The Future of AI at Work - with Nicholas Thompson and Matt Wood

28 min29 oktober 2025

What does it take to succeed in the disruptive world of AI? In this episode, Atlantic CEO Nicholas Thompson sits down with Matt Wood, PwC’s Global  and U.S. Commercial Technology and Innovation Officer, to trace his path from medical school and protein folding research to Amazon Web Services and now PwC. They discuss the transformative power of AI; why, when disruptive forces emerge, companies may be better off doubling down on their core identity rather than reinventing themselves; and how the organizations of the future may be reshaped by autonomous agents working alongside humans.


(00:00) Introduction

(02:16) Matt's path from medicine to machine learning

(05:47) The Human Genome Project and the data explosion

(09:28) The AI inflection point

(11:41) Why AI’s biggest impact will be organizational, not technical

(13:30) How companies navigate disruption without losing identity

(19:18) The coming flattening of organizations

(22:02) Managing teams of humans and agents

(25:41) The most interesting way Matt has used AI

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