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The Primal Podcast

Ep 160 - Dr Jamnadas | What Happens If You Don’t Eat For 36 Hours?

1 tim 10 min7 juni 2026

This episode is brought to you by the⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Primal Tallow Soaps & Balms.⁠⁠⁠⁠⁠⁠⁠⁠

Join us as cardiologist Dr. Pradip Jamnadas (MD) explains the link between chronic inflammation and visceral fat. In this episode, we explore how high insulin levels act as a metabolic brake, preventing fat oxidation and cellular renewal. Dr. Jamnadas shares his vast cardiovascular expertise to explain the science of cellular autophagy and why prolonged fasting is a clinical powerhouse for cellular repair.

By shifting the focus from calories to hormonal optimization, this episode offers a masterclass in preventative medicine. This episode is essential for anyone interested in the science of fasting, both intermittent fasting and the magic of the 36 hour fast, and how it can improve metabolic flexibility. 


In This Episode, We Reveal:

  • The Dangers of Visceral Fat: A clinical review of why ectopic fat storage in the abdominal cavity is the primary driver of systemic inflammation and cardiovascular disease.
  • The Insulin-Adipose Connection: Understanding the hormonal "lock" that prevents the mobilization of stored energy and how fasting restores insulin sensitivity.
  • Autophagy & Cellular Maintenance: A scientific breakdown of the body’s innate repair mechanism and the specific fasting durations required to trigger protein recycling.
  • The "Starvation" Myth vs. Clinical Fasting: Differentiating between nutrient deprivation and the controlled, physiological state of metabolic switching.
  • Electrolytes & Metabolic Support: Why sodium, magnesium, and potassium are non-negotiable for maintaining cardiovascular stability during extended fasting windows.
  • Worst foods: Identifying the "healthy" processed foods that trigger metabolic dysfunction and the four nutrient-dense pillars of health.

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