4 Precautions to Take When Prescribing Opioids for Refractory Restless Legs Syndrome

Restless legs syndrome (RLS) that is unresponsive to traditional therapies or in which the patients can’t tolerate traditional therapies—can be frustrating for clinicians and patients alike. Opioids can be a viable therapy for these patients—and a paper published in the January 2018 issue of Mayo Clinic Proceedings aims to illuminate this treatment pathway.