Ep. 176: “Stem Cells and the Skin” Featuring Dr. Valerie Horsley

Guest:

Dr. Valerie Horsley is an Associate Professor of Molecular, Cellular, and Developmental Biology, and Associate Professor of Dermatology at Yale University. Her lab studies how adult stem cells within epithelial tissues maintain tissue homeostasis, wound healing and can contribute to cancer formation.

Featured Products and Resources:

• Webinar: Building Brain Organoids and Assembloids to Study Human Development and Disease
• Dermal Cell News

The Stem Cell Science Round Up

Treating Obesity and Diabetes with CRISPR-Engineered Fat Cells – White adipocytes were engineered to resemble heat-generating brown fat cells. Transplantation prevented diet-induced obesity and improved glucose homeostasis in mice.

A Map of Embryonic Mouse Foregut Development – Scientists have traced the signaling network of endoderm-mesoderm interactions that orchestrate mouse foregut organogenesis.

Mechanisms of Trachea Formation – Scientists found that bidirectional Wnt signaling between endoderm and mesoderm promotes trachea development.

Scarless Wound Healing – An FDA-approved cream used to treat skin cancers and warts promoted scarless tissue regeneration in wounded mice.

Photo Reference: Courtesy of Dr. Valerie Horsley