Ep. 178: “Muscle Stem Cell Quiescence” Featuring Dr. Tom Cheung

Guest:

Dr. Tom Cheung is an S H Ho Associate Professor of Life Science at the Hong Kong University of Science and Technology. His lab investigates the molecular pathways that control muscle stem cell quiescence and stem cell-mediated tissue regeneration.

Featured Products and Resources:

• Muscle Cell News
• STEMCELL Technologies Human MyoCult™ Workflow

The Stem Cell Science Round Up

Organoid Model of Rare Genetic Disorder – Scientists generated organoids from individuals 22q11.2 deletion syndrome. They found defects in electrical activity, and identified a possible target to rescue phenotypes associated with the disease.

Susceptibility of SARS-CoV-2 Infection in Brain Organoids – hiPSC-derived brain organoids were used to investigate the ability of SARS-CoV-2 to infect brain cells. The susceptibility to infection was low for neurons and astrocytes, but high for choroid plexus epithelial cells.

Mapping the Human Heart – Investigators used transcriptomic data to characterize six anatomical adult heart regions, creating the most extensive cell atlas of the human heart to date.

A Contributor to Fanconi Anemia – Scientists found that high levels of MYC expression promote proliferation and DNA damage in hematopoietic stem and progenitor cells in individuals with Fanconi anemia.

Photo Reference: Courtesy of Dr. Tom Cheung