Ep. 226: “The ‘Egg to Embryo’ Transition” Featuring Dr. Edward Grow

Guest:

Dr. Edward Grow is an Assistant Professor at the University of Texas, Southwestern. His lab studies reproductive biology, specifically the development of the egg and subsequently the fertilized embryo. He talks about regulating totipotency in ESCs, retroviral reactivation, and ex vivo culturing of follicles and oocytes.

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The Stem Cell Science Round Up

Controlling Cell State Transitions – Researchers developed a model that identifies the core signaling networks controlling cell fate transitions.

Modeling Human Heart Development – Scientists used single-cell RNA sequencing to examine the subtypes of cardiomyocytes in the mammalian heart.

Fetal HSC Expansion and Differentiation – Researchers used in vivo genetic tracing in mice to analyze the formation of HSCs and progenitors from intra-arterial hematopoietic clusters.

T Cells in Humanized Mice – Mice engrafted with human thymus organoids can serve as a new animal model to study human T cell-mediated immunity.

Photo Reference: Courtesy of Dr. Edward Grow