Ep. 265: “RNA Glycosylation” Featuring Dr. Ryan Flynn

Guest:

Dr. Ryan Flynn is a Principal Investigator at Boston Children’s Hospital and an Assistant Professor in the Stem Cell and Regenerative Biology Department at Harvard University. His lab explores the interface between RNA and glycans. He talks about the discovery of glycoRNA and the chemistry of the RNA-glycan connection. He also discusses the effects of glycans on stem cell function and deciding between a career in medicine and basic science.

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The Stem Cell Science Round Up

Modeling Traumatic Brain Injury – Researchers used mechanically injured organoids to identify a target to reduce neuronal death after brain injury.

Spinal Cord Organoid Regeneration – The regenerative capabilities of the neonatal spinal cord may be due to proteins in the extracellular matrix.

HSC Transplantation to Treat HIV – Scientists developed a gene editing strategy targeted for autologous HSPC transplantation as a functional cure for HIV.

Hepatocyte Organoids to Treat Liver Failure – Encapsulated liver organoids rescued mice from liver failure.

Image Courtesy of Dr. Ryan Flynn