Ep. 286: “Neural Lineage Identity” Featuring Dr. Marius Wernig

Guest:

Dr. Marius Wernig is a Professor of Pathology and a Co-Director of the Institute for Stem Cell Biology and Regenerative Medicine at Stanford University, where his research interests include direct reprogramming and neurological disease modeling. He talks about his early work reprogramming neuronal cells from fibroblasts, adopting iPSCs, and growing his lab. He also discusses his recent research on cell therapy for brain and skin diseases, as well as his musical talents outside of the lab. (39:58)

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The Stem Cell Science Round Up

Transplanting a Pig Heart – Researchers transplanted a gene-edited porcine heart into a patient with heart failure. (1:53)

Regeneration after Viral Infection – Using single-cell transcriptomics and lineage tracing, scientists examined mouse lung regeneration after influenza. (13:18)

Human Brain Development – A new single-cell atlas sheds light on the molecular and cellular dynamics of the developing human neocortex. (21:38)

The Nuclear Matrix in hSPCs – Heterogeneous nuclear ribonucleoprotein U promotes the primed state in hPSCs. (30:40)

Image courtesy of Dr. Marius Wernig