Ep. 304: “Gene Regulation” Featuring Dr. Lars Velten

Guest:

Dr. Lars Velten is a Group Leader at the Centre for Genomic Regulation in Barcelona. He talks about his research on cell-state-specific enhancers in hematopoiesis and lineage tracing techniques to study blood aging. He also discusses combining generative AI with wet lab techniques and the advantages of risk-taking in basic research. (40:41)

Featured Products and Resources:

• StemSpan™ Hematopoietic Cell Media and Supplements
• Explore educational resources to help you further your research on hematopoiesis and hematological malignancies.

The Stem Cell Science Round Up

HSPC Aging in Space – Spaceflight reduces telomere maintenance and HSPC self-renewal. (1:50)

Modeling Myelin Repair – Brain organoids with integrated microglia enabled the investigation of demyelination and remyelination. (14:45)

Gastric Cancer Organoids – CRISPR screens with human tumor organoids revealed metabolic dependencies and synthetic lethal pairs. (25:55)

Gastroids to Model Stomach Development – This study reveals a principle for instructing gastric patterning and provides a platform for advancing knowledge of stomach organogenesis. (33:10)

Image courtesy of Dr. Lars Velten