Episode 17: Decoding Time of Death: The Post-Mortem Interval and Toxicology Challenges

Interpreting toxicology results after death isn’t always straightforward—especially when time is a factor. In this episode, we discuss the post-mortem interval (PMI) and how it complicates toxicological interpretation. We explore how decomposition affects drug concentrations and why traditional methods of estimating PMI have limitations. Could omics-based approaches, like metabolomics and proteomics, offer a more accurate way to determine time of death? Tune in as we break down the science behind PMI and its impact on forensic toxicology. Hope you enjoy! Disclaimer: All opinions are our own. Find us on instagram: @the_tox_lab Email us here: [email protected] Links to the paper we discussed: https://pmc.ncbi.nlm.nih.gov/articles/PMC11817326/